Clinical practice guidelines: the use of growth hormone in children and adults. Manual. Health Technology Assessment Unit, Putrajaya, Malaysia. (2010)
Abstract
Growth hormone (GH) has been used in clinical practice since 1950s. The initial source of GH was human cadaver pituitary extract. The supply was scarce and the scope of GH usage then was limited only to children with proven GH deficiency. In 1985, pituitary-derived GH was banned because of its association with Creutzfeld Jacob disease. This triggered an acceleration in the biosynthesis of GH via recombinant DNA technology. Today there is an abundant supply of biosynthetic GH commercially. The use of GH has also expanded markedly beyond GH deficiency to conditions without GH deficiency where data regarding its efficacy and safety in these conditions are still lacking.
| Item Type: | Monograph (Manual) |
|---|---|
| Keywords: | Growth hormone, Growth disorders, rhGH therapy, Stunted growth, Pediatric nursing |
| Taxonomy: | By Subject > Health Sciences > Nursing |
| Local Content Hub: | Subjects > Health Sciences |
| Depositing User: | Farleen Azrina Zamberi |
| Date Deposited: | 04 Jul 2022 04:13 |
| Last Modified: | 04 Jul 2022 04:13 |
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