Clinical practice guidelines: management of immune thrombocytopenic purpura. Manual. Health Technology Assessment Unit, Putrajaya, Malaysia. (2006)
Abstract
Immune thrombocytopenic purpura (ITP) affects both children and adults. It is an autoimmune disorder characterised by persistent thrombocytopenia (peripheral platelet count of less than 150 x10 /L) due to autoantibody binding to platelet antigen(s) causing their premature destruction by the reticuloendothelial system, in particular the spleen. In childhood, the peak age is 2-4 years, girls and boys are equally affected, and in most children the disease is self-limiting with spontaneous recovery occurring in several weeks to several months. In adults, ITP is most common among young women and the disease is more insidious in its onset and chronic in its course. The true incidence of ITP is still unknown. In children, the overall incidence of ITP is 4 – 5.3 per 100,000. It has been reported that the incidence of chronic adult ITP is around 5.8-6.6 new cases per 100,000 population per year in the USA.
| Item Type: | Monograph (Manual) |
|---|---|
| Keywords: | Immune thrombocytopenia, Mucocutaneous bleeding, Autoimmune disorder, Full blood count |
| Taxonomy: | By Subject > Health Sciences > Medical Lab Technology > Hematology |
| Local Content Hub: | Subjects > Health Sciences |
| Depositing User: | Farleen Azrina Zamberi |
| Date Deposited: | 05 Jul 2022 04:31 |
| Last Modified: | 05 Jul 2022 04:31 |
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