Kelulut honey improves folliculogenesis, steroidogenic, and aromatase enzyme profiles and ovarian histomorphology in letrozole-induced polycystic ovary syndrome rats. Nutrients, 14 (20). pp. 1-17. ISSN 2072-6643 (2022)
Abstract
Polycystic ovary syndrome (PCOS) has been linked to aberrant folliculogenesis and abnormalities in the aromatase enzyme (Cyp19a1) and the steroidogenic enzyme, 17-alpha-hydroxylase (Cyp17a1) expression. It has been demonstrated that Kelulut honey (KH) improves both female and male reproductive system anomalies in animal studies. Here, we examined the effects of isolated and combined KH, metformin, and clomiphene in improving folliculogenesis, aromatase, and steroidogenic enzyme profiles and ovarian histomorphology in letrozole-induced PCOS rats.
| Item Type: | Article |
|---|---|
| Keywords: | Kelulut Honey, Folliculogenesis, Steroidogenic, Aromatase, PCOS |
| Taxonomy: | By Niche > Kelulut (Stingless Bee) > Physiology By Niche > Kelulut (Stingless Bee) > Products Therapeutic Use |
| Local Content Hub: | Niche > Kelulut (Stingless Bee) |
| Depositing User: | Nor Azimahwati Aris |
| Date Deposited: | 15 Sep 2023 08:07 |
| Last Modified: | 15 Sep 2023 08:07 |
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