Kelulut honey regulates sex steroid receptors in a polycystic ovary syndrome rat model. International Journal of Molecular Sciences, 23 (23). pp. 1-17. ISSN 1422-0067 (2022)
Abstract
Reproductive and metabolic anomalies in polycystic ovary syndrome (PCOS) have been associated with the dysregulation of sex steroid receptors. Kelulut honey (KH) has been shown to be beneficial in PCOS-induced rats by regulating folliculogenesis and the oestrus cycle. However, no study has been conducted to evaluate KH’s effect on sex steroid receptors in PCOS. Therefore, the current study examined the effects of KH, metformin, or clomiphene alone and in combination on the mRNA expression and protein distribution of androgen receptor (AR), oestrogen receptor α (ERα), oestrogen receptor β (ERβ), and progesterone receptor (PR) in PCOS-induced rats.
| Item Type: | Article |
|---|---|
| Keywords: | Honey, PCOS, Oestrogen receptors, Androgen receptor, Progesterone receptor |
| Taxonomy: | By Niche > Kelulut (Stingless Bee) > Products Therapeutic Use By Niche > Kelulut (Stingless Bee) > Research |
| Local Content Hub: | Niche > Kelulut (Stingless Bee) |
| Depositing User: | Nor Azimahwati Aris |
| Date Deposited: | 15 Sep 2023 08:27 |
| Last Modified: | 15 Sep 2023 08:27 |
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