Effect of kelulut honey on the cellular dynamics of TGFβ-induced epithelial to mesenchymal transition in primary human keratinocytes

Effect of kelulut honey on the cellular dynamics of TGFβ-induced epithelial to mesenchymal transition in primary human keratinocytes. International Journal of Environmental Research and Public Health, 17 (9). pp. 1-15. ISSN 1660-4601 (2020)



Abstract

Over-induction of epithelial to mesenchymal transition (EMT) by tumor growth factor beta (TGFβ) in keratinocytes is a key feature in keloid scar. The present work seeks to investigate the effect of Kelulut honey (KH) on TGFβ-induced EMT in human primary keratinocytes. Image analysis of the real time observation of TGFβ-induced keratinocytes revealed a faster wound closure and individual migration velocity compared to the untreated control.

Item Type: Article
Keywords: Honey, Migration, Wound healing, Cell morphology, Scratch assay, Keloid scar
Taxonomy: By Niche > Kelulut (Stingless Bee) > Products Therapeutic Use
By Niche > Kelulut (Stingless Bee) > Research
Local Content Hub: Niche > Kelulut (Stingless Bee)
Depositing User: Nor Azimahwati Aris
Date Deposited: 15 Sep 2023 08:36
Last Modified: 15 Sep 2023 08:36
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