Computer Based Characterisation of Pteropus vampyrus Endogenous Betaretrovirus (PvEB) from bat genome project database. In: 2014 IEEE Symposium on Computer Applications and Industrial Electronics (ISCAIE), 07-08 April 2014, Penang, Malaysia. (In Press) (2015)
Abstract
Retroviruses have been associated with numerous chronic diseases such as leukemias and immunodeficiencies which harbored by diverse host range of animals. Recently, one member of bat endogenous retrovirus has been reported as the basal of gammaretrovirus. Later, a study discovered that betaretrovirus also present in diverse micro and megabats. From these recent studies, we gain our interest to further analyze one of the discoveries of betaretrovirus in Pteropus vampyrus in which we called it as Pteropus vampyrus endogenous betaretrovirus (PvEB). The size of nucleotide sequence is 8.7kb which was obtained during screening and characterization of bat genome from large flying fox (Pteropus vampyrus) database genome project. It has a typical genomic organization of a retrovirus possessing all the major conserved motifs and LTR flanking the viral genes:5’-LTR-gag-dUTPasepol-env-LTR-3’plus the presence of dUTPase which is common in all betaretrovirus. Therefore, this discovery strengthens the current studies which extend the endogenous retrovirus from bats into betaretrovirus group.
| Item Type: | Conference or Workshop Item (Paper) |
|---|---|
| Keywords: | Bat, Pteropus vampyrus, Endogenous betaretrovirus, Genomic |
| Taxonomy: | By Niche > Genome > Animal Genome Mapping By Niche > Genome > Viral Genomes |
| Local Content Hub: | Niche > Genome |
| Depositing User: | Hazrul Amir Tomyang (Puncak Alam) |
| Date Deposited: | 01 Apr 2024 08:46 |
| Last Modified: | 01 Apr 2024 08:46 |
| Related URLs: |
Actions (login required)
 |
View Item |