Application and modification of RT-LAMP for rapid detection of SARS-CoV-2 viral genome

Application and modification of RT-LAMP for rapid detection of SARS-CoV-2 viral genome. The Malaysian Journal of Medicine and Health Sciences (MJMHS), 19 (2). pp. 286-292. ISSN 2636-9346 (2023)



Abstract

COVID-19 outbreak caused by the newly discovered SARS-CoV-2 has become a major public health threat around the world and has create a tremendous effect on the global economy. Hence, there is a high demand for rapid and accurate diagnosis to contain the spread of the disease. The Reverse-Transcription Polymerase Chain Reaction (RTPCR), the current standard for diagnosis of COVID-19 however possesses certain drawbacks that limits its application to meet the high demand of the continually increasing COVID-19 cases. Conversely, Loop-Mediated Isothermal Amplification (LAMP) is another nucleic acid amplification method that shows a great potential as an alternative tool in rapid diagnosis of COVID-19 due to its simplicity and rapidity. This review summarized the recent published research articles related to the application and modification of RT-LAMP assay for the rapid detection of COVID-19 in comparison with other available diagnostic methods.

Item Type: Article
Keywords: RT-LAMP, RT-PCR, COVID-19, SARS-CoV-2
Taxonomy: By Niche > Genome > Microbial Genomes
By Niche > Genome > Viral Genomes
Local Content Hub: Niche > Genome
Depositing User: Hazrul Amir Tomyang (Puncak Alam)
Date Deposited: 01 Apr 2024 08:50
Last Modified: 01 Apr 2024 08:50
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