Pharmacogenomics of CYP2D6: molecular genetics, interethnic differences and clinical importance. Drug Metabolism and Pharmacokinetics, 27 (1). pp. 55-67. ISSN 1880-0920 (2012)
Abstract
CYP2D6 has received intense attention since the beginning of the pharmacogenetic era in the 1970s. This is because of its involvement in the metabolism of more than 25% of the marketed drugs, the large geographical and inter-ethnic differences in the genetic polymorphism and possible drug-induced toxicity. Many interesting reviews have been published on CYP2D6 and this review aims to reinstate the importance of the genetic polymorphism of CYP2D6 in different populations as well as some clinical implications and important drug interactions.
| Item Type: | Article |
|---|---|
| Keywords: | CYP2D6 polymorphism, Interethnic differences, Clinical implication |
| Taxonomy: | By Niche > Genome > Human Genome Research |
| Local Content Hub: | Niche > Genome |
| Depositing User: | Hazrul Amir Tomyang (Puncak Alam) |
| Date Deposited: | 27 May 2024 09:22 |
| Last Modified: | 27 May 2024 09:22 |
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