Genomic-informed Initiative on Surveillance of MDR-TB in Malaysia. UNSPECIFIED. UiTM, Integrative Pharmacogenomic Institute (iPROMISE). (2024)
Abstract
• Tuberculosis is still a major health problem in Malaysia with
thousands of cases reported yearly along with the emergence of multi-drug resistance tuberculosis (MDR-TB)1.
• Identification and prediction of MDR-TB are important to ensure efficient TB management2.
• Online annotation tools to analyse Mycobacterium tuberculosis complex (MTBC) genomes had been published for public use.
• Having local MTBC genome database allows identification of drug resistant variants which could be used to design diagnostic kits for detection of drug-resistant MTB.
• The current study is an initial effort in establishing MTBC genome database in Malaysia and demonstrates the application of the database in discovering the genetic diversity of the clinical MTBC isolates.
| Item Type: | Monograph (UNSPECIFIED) |
|---|---|
| Keywords: | Tuberculosis (TB), MDR-TB (Multi-drug Resistant Tuberculosis), Mycobacterium tuberculosis complex (MTBC), Genome database |
| Taxonomy: | By Niche > Genome > Bacterial Genomes By Niche > Genome > Genomes Data Processing By Niche > Genome > Microbial Genomes |
| Local Content Hub: | Niche > Genome |
| Depositing User: | Hazrul Amir Tomyang (Puncak Alam) |
| Date Deposited: | 30 May 2025 01:58 |
| Last Modified: | 30 May 2025 01:58 |
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