Chemical composition and biological activity of the centipeda minima (Asteraceae). Malaysian Journal of Nutrition, 13 (1). pp. 81-87. ISSN 1394-035X (2007)
Abstract
The antimicrobial activity of the Centipeda minima L. (Asteraceae) extract was evaluated against seven microorganisms using the disc diffusion method. The extract showed a broad spectrum of antimicrobial activity against all the tested bacterial strains, especially Enterobacter aerogenes, Klebsiella pneumonia, Staphylococcus aureus and Yersinia enterocolitica. The chemical composition of the extract obtained from Centipeda minima was analysed by GC–MS. Twentythree compounds, constituting about 84.75 % of the total extract, were identified. The main constituents were palmitic acid (7.47%), (Z,Z)-9-,12-octadecatrienoic acid (6.52%), (Z,Z,Z)-9-,12-octadecatrienoic acid (7.01%), phytol (7.01%), naptho[2.3-b]furan-2-(3H)-on (6.21%), 1-(1,2,3,4,7,7a-hexahydro1,4,4,5-tetramethyl-1,3a-ethano-3aH-inden-6-yl)etanon (7.95%), 1,3,5-tri-tertbutyl-benzene (4.52%), (3Z)-2-methyl-3-octen-2-ol (5.95%) and artemisia ketone (4.98%). The extract was also tested against brine shrimp for toxicity. There was no significant toxicity as it only recorded a LC50 value of 4.92 mg/ml. The study shows that the extract is a good antimicrobial agent with potential applications in public health against diseases.
| Item Type: | Article |
|---|---|
| Keywords: | Antimicrobial activity, Microorganisms, Centipeda minima L. (Asteraceae), Antimicrob |
| Taxonomy: | By Subject > Applied Sciences > Biology |
| Local Content Hub: | Subjects > Applied Sciences |
| Depositing User: | Mohd Hafiz Kasirun |
| Date Deposited: | 30 Apr 2021 05:07 |
| Last Modified: | 30 Apr 2021 05:07 |
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