Association of Red Blood Cell Transfusion with Mortality and Morbidity in Post Cardiac Surgery Patients

Association of Red Blood Cell Transfusion with Mortality and Morbidity in Post Cardiac Surgery Patients. Malaysian Journal of Medicine and Health Sciences, 14 (SUPP1). pp. 28-33. ISSN 2636-9346 (2018)



Abstract

Introduction: CAD accounts for 25% of mortality in Malaysia public hospitals. CABG is one of treatment for patientswith CAD, but requires RBC transfusion, which is associated with morbidity and mortality. This study was to evaluate the association between RBC transfusion and morbidity and mortality in CABG patients at the National Heart
Centre, Malaysia (IJN).

Methods: Retrospective cross-sectional study performed using data from 434 patients who underwent CABG in 2013 and 2014. Subjects had systematic random sampling every fifth subject of the patients in the sequence of dates of the year. Data related to the relationship between RBC transfusion with mortality and
morbidity, and the predicting factors captured.

Results: 64.3% of CABG patients (n = 279) received RBC transfusion perioperatively. Age, gender, BMI, and EF, were factors that contributed for RBC transfusion. RBC transfusion was a contributor to longer intensive care unit length of stay (ICULOS) and hospital length of stay (HLOS). Multiple logistic regression revealed, for every 1 year increase of age, there is 3.5% higher chance of transfusion. Whereas an
increase of 1 kg/m2 of BMI and 1% of EF reduced the odds of RBC transfusion by 13.0% and 3.0% respectively.

Conclusions: Age, gender, BMI, and EF determine the probability of needing RBC transfusion during CABG, and RBC transfusion will result in longer ICULOS, and HLOS. Probability of RBC transfusion will be higher in older patients and reduced in those with higher BMI and EF.

Item Type: Article
Keywords: CAD, CABG, RBC transfusion, Morbidity, Mortality
Taxonomy:
Agencies of Resources: Higher Institution > Public University > Universiti Putra Malaysia > UPM-MTDC Technology Center | JTS & JSSH Only | UPM/TNCPI/UPM-JD/LibraryUiTM - 16/11/2018
Local Content Hub: Subjects > Medicine
Depositing User: Asnida Md Arop (Sg. Buloh)
Date Deposited: 07 Oct 2021 23:33
Last Modified: 07 Oct 2021 23:33
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