Effects of Using Two Different Dosing of Propofol as an Induction Agent in Patients Undergoing Electro Convulsive Therapy (ECT) at the Psychiatric Department, Hospital Kuala Lumpur. Malaysian Journal of Medicine and Health Sciences, 17 (SUPP4). pp. 40-47. ISSN 2636-9346 (2021)
Abstract
Introduction: Electroconvulsive therapy (ECT) is one of the treatments in treating psychotic disorders. Indications for ECT are major depressive disorder, bipolar mood disorder, and schizophrenia. Propofol reduces the seizure activity for those patients who underwent the ECT. Still, considering the dose of propofol given by using a lower dosage of propofol based on recommended doses, it might increase seizure activity quality without harmful effects on the patients.
Methods: A retrospective study was conducted to evaluate the seizure duration, quality of EEG, postictal suppression, and recovery time in 200 patients undergoing ECT treatment who were sedated with either low dose (<1.5 mg/kg) or high dose (> 1.5 mg/kg) of propofol at Psychiatric Department, Hospital Kuala Lumpur between June 2016 to June 2017. All the results were analyzed with the statistical software SPSS (v. 22.0).
Results: Based on the finding in this study, the group of who received propofol at less than 1.5 mg/kg tend to get longer seizure motor duration compared to the group of more than 1.5 mg/kg. The result showed the mean duration of motor seizure in the group at less than 1.5 mg/kg of propofol is significantly higher than the group of more than 1.5 mg/kg.
Conclusions: Thus, it is essential to titrate propofol using propofol towards the patients undergoing the ECT procedure and using a lower dose of propofol.
| Item Type: | Article |
|---|---|
| Keywords: | Anesthesia, Electroconvulsive therapy, Propofol |
| Taxonomy: | By Subject > Medicine > Psychiatry |
| Local Content Hub: | Subjects > Medicine |
| Depositing User: | Asnida Md Arop (Sg. Buloh) |
| Date Deposited: | 11 Oct 2021 23:34 |
| Last Modified: | 11 Oct 2021 23:34 |
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