Prevalence of dyslipidaemia in type 2 diabetes mellitus patients and its association to diabetic retinopathy in a Malaysian tertiary hospital

Prevalence of dyslipidaemia in type 2 diabetes mellitus patients and its association to diabetic retinopathy in a Malaysian tertiary hospital. Malaysian Journal of Medicine and Health Sciences, 10 (2). pp. 47-51. ISSN 1675-8544 (2014)



Abstract

Background: Diabetic retinopathy (DR) is a microvascular complication of diabetes, which is a cause of visual impairment and blindness. Its development and progression have been linked to dyslipidaemia, although the link remains inconclusive.

Aim: This study aimed to determine the prevalence of dyslipidaemia among type 2 diabetic patients with DR in a tertiary setting and to determine the association between dyslipidaemia and DR severity.

Materials and methods: This was a cross sectional study using retrospective data of type 2 diabetic patients attending the opthalmology clinic of a tertiary centre from January 2007 to June 2014. Results of their fasting lipid profile and clinical data were retrieved from the hospital information system.

Results: A total of 178 patient’s data were collected. 120 (n=67.4%) patients had non-proliferative diabetic retinopathy (NDPR) with moderate NPDR being the most prevalent. Dyslipidaemia was noted in 151 (84.8%) of the patients. Patients had a combination of more than one abnormality in the lipid profile with increased LDL-cholesterol being the main abnormality. Dyslipidaemia was however, not significantly associated with DR severity.

Conclusion: Dyslipidaemia was highly prevalent in DR patients. The dyslipidaemia was however not associated with severity of DR.

Item Type: Article
Keywords: Diabetic retinopathy, Dyslipidaemia, Non-proliferative diabetic retinopathy, Proliferative diabetic retinopathy, Type 2 diabetes mellitus
Taxonomy: By Subject > Medicine > Endocrine System
By Subject > Medicine > Ophthalmology
Local Content Hub: Subjects > Medicine
Depositing User: Adi Azri Mohamad (Sg. Buloh)
Date Deposited: 15 Feb 2022 23:31
Last Modified: 16 Feb 2022 02:39
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