Successful conservative treatment of massive infective endocarditis with severe mitral valve regurgitation and septic emboli

Successful conservative treatment of massive infective endocarditis with severe mitral valve regurgitation and septic emboli. Malaysian Journal of Medicine and Health Sciences, 17 (3). pp. 315-318. ISSN 2636-9346 (2021)



Abstract

Management of complicated massive infective endocarditis (IE) in patients who are contraindicated for surgical valve replacement has long been a dilemma for many clinicians. Studies have shown that massive IE patients who were treated conservatively generally result in poorer prognosis. We report two cases of massive native valve infective endocarditis with severe mitral valve regurgitation and septic emboli that has been successfully treated conservatively. Interestingly, despite having a large vegetation and multiple septic emboli complications, none of these two cases had any positive culture or serology. Managing culture negative IE without surgical intervention pose an even greater challenge to the choice and duration of antibiotics with further long-term plans. We hope to share these case series to aid in the management dilemma of similar cases in the future.

Item Type: Article
Keywords: Massive infective endocarditis, Culture negative, Conservative, Complicated, Septic emboli
Taxonomy: By Subject > Medicine > Cardiovascular System
By Subject > Medicine > Surgery
Local Content Hub: Subjects > Medicine
Depositing User: Adi Azri Mohamad (Sg. Buloh)
Date Deposited: 16 Feb 2022 23:44
Last Modified: 16 Feb 2022 23:44
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