Evaluation of fortimicin antibiotic combinations against MDR Pseudomonas aeruginosa and resistome analysis of a whole genome sequenced pan-drug resistant isolate

Evaluation of fortimicin antibiotic combinations against MDR Pseudomonas aeruginosa and resistome analysis of a whole genome sequenced pan-drug resistant isolate. BMC Microbiology, 24 (164). ISSN 1471-2180 (2024)



Abstract

Multidrug-resistant (MDR) P. aeruginosa is a rising public health concern, challenging the treatment of such a ubiquitous pathogen with monotherapeutic anti-pseudomonal agents. Worryingly, its genome plasticity contributes to the emergence of P. aeruginosa expressing different resistant phenotypes and is now responsible for notable epidemics within hospital settings. Considering this, we aimed to evaluate the synergistic combination of fortimicin with other traditional anti-pseudomonal agents and to analyze the resistome of pan-drug resistant (PDR) isolate.

Item Type: Article
Keywords: MDR P. Aeruginosa, Fortimicin, Resistome analysis, PDR P. Aeruginosa
Taxonomy: By Niche > Genome > Genomes
Local Content Hub: Niche > Genome
Depositing User: Hazrul Amir Tomyang (Puncak Alam)
Date Deposited: 09 Jul 2025 06:39
Last Modified: 09 Jul 2025 06:39
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